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Its design illustrates a radical peptidomimetic : only two amino acid residues (Tyr-Ile) are preserved from the native peptide, flanked by non-peptide acyl chains to cross biological barriers
Most patients need a dose review with their provider every 4 weeks during titration
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Common side effects of Wegovy HD and regular Wegovy include: Nausea Vomiting Diarrhea Constipation Stomach upset In clinical trials, gastrointestinal side effects were more common with Wegovy HD
It is also not recommended for patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
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